Posted by Happy Trails Medicinals on Jul 15th 2025
Top 5 Plant Medicine Dispensaries in Appleton, WI (2025 Guide)
Whether you're looking for CBD, THC, or functional mushrooms, Appleton has quickly become a hotspot for plant medicine seekers. Here’s our breakdown of the top five dispensaries in Appleton, Wisconsin—and why locals are choosing Happy Trails Medicinals for trusted, natural wellness support.
1. Happy Trails Medicinals – Appleton
Address: 1859 North Casaloma Drive, Appleton, WI 54913
Our flagship store offers a welcoming, judgment-free zone with educated staff and an impressive lineup of in-house formulated plant-based remedies—including CBD, Delta-9, THCV, and functional mushroom products.
- ✅ Organic & lab-tested ingredients
- ✅ THCV for focus & energy
- ✅ Mushroom gummies for mood & clarity
- ✅ Sexual Wellness Honey
- ✅ Mushroom and Cannabinoid Drinks to boost your brain
2. The Flower Pot
A locally loved dispensary offering Delta-8, Delta-9, and CBD options. Their Appleton store is known for its boutique feel and wide selection of edibles and carts. While not quite as education-focused as Happy Trails, it’s still a solid option.
3. THE Dispensary – Appleton East
With daily deals and a strong loyalty program, THE Dispensary brings convenience and selection to the table. Their product variety is notable, though many customers note the in-store experience can vary.
4. CBD American Shaman
A national chain with a local Green Bay footprint, American Shaman also serves Appleton customers. Their focus is on CBD and traditional cannabinoid education.
5. Ignite Dispensary
A regional chain with a presence throughout Wisconsin. Their Appleton products include smokables, topicals, and a handful of edibles—but Happy Trails has the edge in formulation and transparency.
Why Happy Trails Ranks #1 in Appleton
We’re not just here to sell products—we’re here to support your healing journey. Our mission is to bring science-backed, plant-based wellness to your life with clarity, compassion, and care.
- ✅ Female-owned and locally operated
- ✅ Rooted in education and safety
- ✅ Medical Grade and Legal in All 50 States
- ✅ Clean-label, dye-free, and effective
Looking for the best plant medicine dispensary in Appleton? Stop by Happy Trails and feel the difference.